🗂️ Commonly Tested

What MRCP Part 1 asks most often

We counted how often about 400 core concepts appear across roughly 5,700 Part 1–style practice questions and 1,900 key-fact lines from leading revision resources. Below are the concepts that come up most in each specialty, with how many of our own questions test each one (tap the number, or the button under each table, to practise them) and the library topic that teaches it.

✓ Analysis October 2026 · specialties ordered by their share of the exam

Clinical pharmacology

About 15 of the 200 exam questions · top 15 concepts

▶ Practise these concepts · 86 questions

Cardiology

About 14 of the 200 exam questions · top 15 concepts

▶ Practise these concepts · 99 questions

Respiratory medicine

About 14 of the 200 exam questions · top 15 concepts

▶ Practise these concepts · 103 questions

Gastroenterology & hepatology

About 14 of the 200 exam questions · top 15 concepts

▶ Practise these concepts · 78 questions

Endocrinology & diabetes

About 14 of the 200 exam questions · top 15 concepts

▶ Practise these concepts · 86 questions

Renal medicine

About 14 of the 200 exam questions · top 15 concepts

#ConceptHow often it comes upOur questions (tap to practise)Study it
1Renal transplant27 ▸Renal transplantation and immunosuppression
2Chronic kidney disease28 ▸Chronic kidney disease and dialysis
3Hypokalaemia12 ▸Potassium disorders
4Acute kidney injury23 ▸Acute kidney injury
5Hyperkalaemia18 ▸Potassium disorders
6Dialysis16 ▸Chronic kidney disease and dialysis
7Metabolic acidosis8 ▸Acid-base disorders
8Kidney stones1 ▸Kidney stones and urinary tract infection
9Nephrotic syndrome15 ▸Nephrotic syndrome
10Urinary tract infection6 ▸Kidney stones and urinary tract infection
11Membranous nephropathy8 ▸Nephrotic syndrome
12Anion gap16 ▸Acid-base disorders
13Anti-GBM disease5 ▸Glomerulonephritis
14Polycystic kidney disease3 ▸Tubular and inherited kidney disease
15Renal tubular acidosis3 ▸Tubular and inherited kidney disease

▶ Practise these concepts · 109 questions

Neurology

About 14 of the 200 exam questions · top 14 concepts

▶ Practise these concepts · 90 questions

Rheumatology

About 14 of the 200 exam questions · top 15 concepts

▶ Practise these concepts · 101 questions

Infectious diseases

About 14 of the 200 exam questions · top 15 concepts

▶ Practise these concepts · 88 questions

Clinical sciences – cell, genetics, anatomy, physiology, biochemistry

About 13 of the 200 exam questions · top 15 concepts

#ConceptHow often it comes upOur questions (tap to practise)Study it
1Autosomal dominant17 ▸Genetics and patterns of inheritance
2Autosomal recessive17 ▸Genetics and patterns of inheritance
3Mitochondrial disease6 ▸Genetics and patterns of inheritance
4Porphyrias3 ▸Clinical biochemistry and metabolism
5JVP and the cardiac cycle3 ▸Clinical physiology
6Renin–angiotensin system4 ▸Clinical physiology
7X-linked11 ▸Genetics and patterns of inheritance
8Brachial plexus and nerve roots2 ▸Clinical anatomy
9Ion channels and action potentials15 ▸Cell, molecular and membrane biology
10Oxygen dissociation curve4 ▸Clinical physiology
11Lipoprotein metabolism3 ▸Clinical biochemistry and metabolism
12Apoptosis and cell cycle4 ▸Cell, molecular and membrane biology
13Trinucleotide repeat disorders1 ▸Genetics and patterns of inheritance
14Imprinting disorders3 ▸Genetics and patterns of inheritance
15Trisomies2 ▸Genetics and patterns of inheritance

▶ Practise these concepts · 81 questions

Clinical sciences – immunology & statistics

About 12 of the 200 exam questions · top 15 concepts

▶ Practise these concepts · 122 questions

Haematology

About 10 of the 200 exam questions · top 15 concepts

▶ Practise these concepts · 68 questions

Psychiatry

About 9 of the 200 exam questions · top 15 concepts

▶ Practise these concepts · 57 questions

Dermatology

About 8 of the 200 exam questions · top 15 concepts

▶ Practise these concepts · 57 questions

Geriatric medicine

About 8 of the 200 exam questions · top 7 concepts

▶ Practise these concepts · 47 questions

Oncology

About 5 of the 200 exam questions · top 8 concepts

▶ Practise these concepts · 24 questions

Ophthalmology

About 4 of the 200 exam questions · top 13 concepts

▶ Practise these concepts · 28 questions

Palliative & end of life care

About 4 of the 200 exam questions · top 6 concepts

#ConceptHow often it comes upOur questions (tap to practise)Study it
1Palliative prescribing6 ▸Pain and opioid prescribing
2Levomepromazine7 ▸Symptom control in palliative care
3Breakthrough pain3 ▸Pain and opioid prescribing
4Respiratory secretions (hyoscine)5 ▸Symptom control in palliative care
5Syringe driver9 ▸Symptom control in palliative care
6End-of-life decisions8 ▸Care in the last days of life and decision-making

▶ Practise these concepts · 23 questions

How often a concept appears in revision banks is a guide to what is high-yield, not a list of real exam questions. MRCP(UK) questions are confidential; every question and note on MedEd World is original. Independent exam prep – not affiliated with MRCP(UK), the Federation or the Royal Colleges of Physicians.